Power users know that the more you can keep your hands on the keyboard, the faster you can get things done on your Mac. That’s the reason keyboard shortcuts exist, like Command-C to copy text, or Shift-Command-3 to take a screenshot. It’s perfectly acceptable to move your mouse to select the command from a menu, of course, but the keyboard shortcuts are just faster.
Spotlight, like most other OS X apps, has several shortcuts that can help you get around much more quickly.