Apple has just released iOS 6.0.1 for all compatible devices (including the new fourth-generation iPad and iPad mini). Right now, you can get it using the direct download links below, or OTA using Software Update on your iOS device (if you have an iPhone 5, you will have to update your Software Update first by going to General > Software Update, which will install a new Software Update app to your homescreen).
The change log isn’t online yet, but will eventually be here. Improvements include numerous bug fixes, including an issue that prevents the iPhone 5 from updating itself over-the-air, a bug where horizontal lines are shown on the keyboard, sporadic issues with camera flashes, improvements with Wi-Fi reliability for iPhone 5 and 2012 iPod touch, and more.
The changelog and direct download links can be found below: